Changes in Left Ventricular Preload, Afterload, and Cardiac Output in Response to a Single Dose of Mannitol in Neurosurgical Patients Undergoing Craniotomy

Abstract

In conclusion, in patients undergoing craniotomy, TEE demonstrated that a single bolus dose of 20% mannitol (1.0 gm/kg) caused significant but short-duration alterations in LV preload, afterload, and CO without concomitant changes in hemodynamic variables (MAP/HR).