Concepedia

Reactive oxygen species regulate epidermal growth factor-induced vascular endothelial growth factor and hypoxia-inducible factor-1α expression through activation of AKT and P70S6K1 in human ovarian cancer cells

Chang Xia, Jie He, Qiong Zhou, Xianglin Shi, Jing Fang, Bing‐Hua Jiang

Free Radical Biology and Medicine · 2006 · 204 citations · 56 references

DOI

Concepts

References

56

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

G L Wang, Bing‐Hua Jiang, E A Rue et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

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Activation of Vascular Endothelial Growth Factor Gene Transcription by Hypoxia-Inducible Factor 1

Jo A. Forsythe, Bing‐Hua Jiang, Narayan V. Iyer et al. · Molecular and Cellular Biology · 1996 · 4K citations · Full text

, , +15

Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress

Carl LeBel, Harry Ischiropoulos, Stephen C. Bondy · Chemical Research in Toxicology · 1992 · 2.7K citations · Full text

, , +12

HIF‐1α is required for solid tumor formation and embryonic vascularization

Heather E. Ryan · The EMBO Journal · 1998 · 1.6K citations · Full text

, , +14

Epidermal Growth Factor (EGF)-induced Generation of Hydrogen Peroxide

Yun Soo Bae, Sang Won Kang, Min Seok Seo et al. · Journal of Biological Chemistry · 1997 · 1.2K citations · Full text

, , +7