Immunomodulatory activity of Melaleuca alternifolia concentrate (MAC): Inhibition of LPS-induced NF-κB activation and cytokine production in myeloid cell lines

Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase.

Q.W. Xie, Yumiko Kashiwabara, Carl Nathan · Journal of Biological Chemistry · 1994 · 2.2K citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Activation of interleukin-6 gene expression through the NF-kappa B transcription factor.

Towia A. Libermann, David Baltimore · Molecular and Cellular Biology · 1990 · 1.4K citations

Life Sciences, Cell Biology, Molecular Biology +16

Transcriptional profiling of the LPS induced NF-κB response in macrophages

Omar Sharif, Stephanie Raines, Peter Newham et al. · BMC Immunology · 2007 · 502 citations · Full text

Life Sciences, Immunology, Molecular Biology +15

Lipopolysaccharide Induction of the Tumor Necrosis Factor-α Promoter in Human Monocytic Cells

Jin Yao, Nigel Mackman, Thomas S. Edgington et al. · Journal of Biological Chemistry · 1997 · 460 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Terpinen-4-ol, the main component of the essential oil of Melaleuca alternifolia (tea tree oil), suppresses inflammatory mediator production by activated human monocytes

Prue H. Hart, C. Brand, Christine Carson et al. · Inflammation Research · 2000 · 454 citations

Veterinary Medicine, Immunology, Pharmacology +17