Smoothened Mutants Reveal Redundant Roles for Shh and Ihh Signaling Including Regulation of L/R Asymmetry by the Mouse Node

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

Chin Chiang, Ying Litingtung, Eric Lee et al. · Nature · 1996 · 3.1K citations

Life Sciences, Developmental Biology, Genetics +14

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

Yann Echelard, Douglas J. Epstein, Benoit St‐Jacques et al. · Cell · 1993 · 2.2K citations

Life Sciences, Neurobiology, Neuroscience +13

Regulation of Rate of Cartilage Differentiation by Indian Hedgehog and PTH-Related Protein

Andrea Vortkamp, Kaechoong Lee, Beate Lanske et al. · Science · 1996 · 2K citations

Life Sciences, Developmental Biology, Molecular Biology +10

Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

Benoit St‐Jacques, Matthias Hammerschmidt, Andrew P. McMahon · Genes & Development · 1999 · 1.8K citations · Full text

Life Sciences, Cell Biology, Developmental Biology +14

Altered Neural Cell Fates and Medulloblastoma in Mouse <i>patched</i> Mutants

Lisa V. Goodrich, Ljiljana Milenković, Kay M. Higgins et al. · Science · 1997 · 1.7K citations

Life Sciences, Genetics, Molecular Genetics +17