TBX5 Transcription Factor Regulates Cell Proliferation during Cardiogenesis

A series of normal stages in the development of the chick embryo

Viktor Hamburger, Howard L. Hamilton · Journal of Morphology · 1951 · 12.3K citations

Biology, Animal Reproduction, Developmental Biology +10

Mutations in human cause limb and cardiac malformation in Holt-Oram syndrome

Craig T. Basson, David R. Bachinsky, Robert C. Lin et al. · Nature Genetics · 1997 · 1.1K citations

Developmental Anomaly, Cardiac Malformation, Developmental Biology +9

Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family

Newbury-Ecob Ra, David I. Wilson, T Strachan et al. · Nature Genetics · 1997 · 925 citations

Developmental Anomaly, Genetic Disorder, Genetics +6

Expression of the T-box family genes,Tbx1-Tbx5, during early mouse development

Deborah L. Chapman, Nancy Garvey, Sarah Hancock et al. · Developmental Dynamics · 1996 · 656 citations

Chamber-Specific Cardiac Expression of Tbx5 and Heart Defects in Holt–Oram Syndrome

Benoit G. Bruneau, Malcolm Logan, Tatjana Levi et al. · Developmental Biology · 1999 · 506 citations

Heart Defects, Heart Failure, Structural Heart Disease +8