Fio2 and positive end-expiratory pressure as compensation for altitude-induced hypoxemia in an acute respiratory distress syndrome model: Implications for air transportation of critically ill patients

Abstract

Fifty percent of the animals with lung injury had altitude-induced hypoxia that was resistant to increases in FiO2. Increases in positive end-expiratory pressure are more reliable than increases in FiO2 for correcting altitude-induced hypoxia in this model of acute respiratory distress syndrome.