Journal of the American Chemical Society · 2012 · 24 citations · 11 references
Life SciencesBiotechnologyMolecular BiologyNanotechnologyTranscriptionTranscriptional RegulationDna NanotechnologyDna StructureMolecular NanotechnologyNucleic Acid StructureTranscription In EukaryotesAddressable Dna NanostructuresDna NanomaterialsDna Nanostructure AssemblyDna-based Self-assemblyReconfigurable Dna NanostructuresStimuli-responsive Dna NanostructuresToehold-mediated Strand Displacement
A transcription regulation system initiated by DNA nanostructure changes was designed and constructed. Using the toehold system, specific DNA strands induced the opening of the tubular structure. A transcription product from the purified tube-attached dsDNA template was observed by addition of DNA strands that were specific for opening the tubular structure.
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