Concepedia

Pharmacokinetics of piperacillin/tazobactam in cancer patients with hematological malignancies and febrile neutropenia after chemotherapy

José Camilo Álvarez-Rodríguez, Sonia Isabel Cuervo, Javier Garzón, Julio César Gómez, Jorge Díaz, Edelberto Silva, Ricardo Sánchez, Jorge Alberto Cortés

BMC Pharmacology and Toxicology · 2013 · 13 citations · 12 references

DOIFull text

Open access

Abstract

Patients with FN after receiving chemotherapy exhibited significant variations in the pharmacokinetic parameters of piperacillin compared with healthy individuals; specifically, FN patients demonstrated an increase in t1(/2) and decreased CL.

References

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