Concepedia

A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans

Andrew R. Burns, Iain M. Wallace, Jan Wildenhain, Mike Tyers, Guri Giaever, Gary D. Bader, Corey Nislow, Sean R. Cutler, Peter J. Roy

Nature Chemical Biology · 2010 · 188 citations · 34 references

DOI

Concepts

References

34

ZINC − A Free Database of Commercially Available Compounds for Virtual Screening

John J. Irwin, Brian K. Shoichet · Journal of Chemical Information and Modeling · 2004 · 4K citations · Full text

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Integration of biological networks and gene expression data using Cytoscape

Melissa Cline, Michael Smoot, Ethan Cerami et al. · Nature Protocols · 2007 · 2.6K citations · Full text

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The Properties of Known Drugs. 1. Molecular Frameworks

Guy W. Bemis, Mark A. Murcko · Journal of Medicinal Chemistry · 1996 · 2.3K citations

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Reoptimization of MDL Keys for Use in Drug Discovery

Joseph L. Durant, Burton A. Leland, Douglas R. Henry et al. · Journal of Chemical Information and Computer Sciences · 2002 · 1.8K citations

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Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists

B. Evans, Kenneth E. Rittle, Mark G. Bock et al. · Journal of Medicinal Chemistry · 1988 · 1.4K citations · Full text

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