Journal of Paediatrics and Child Health · 1993 · 32 citations · 11 references
MedicineMicrobiologyPediatricsInfant HealthMedical MicrobiologyPediatric Infectious DiseasesNeonatal HematologyNeonatal ImmunologyNeonatal InfectionsNeonatal Infectious DiseasesPerinatal InfectionPlatelet DisordersCandida Albicans InfectionFungal Infections In NewbornsNeonatal Bacterial SepsisNeonatal Bloodstream InfectionNeonatal CandidiasisNeonatal Fungal InfectionNeonatal Susceptibility To InfectionPediatric Thrombocytopenia
The clinical, haematological and microbiological features of 12 extremely low birthweight (ELBW) infants with Candida infection were compared with 36 gestational-age and birthweight matched controls who experienced 42 episodes of bacterial septicaemia. Thrombocytopenia was the feature observed most commonly, occurring in 12 of 12 study infants and 23 of 42 controls (P = 0.004). Minimum platelet counts were below 50 x 10(9)/L in 11 of 12 study patients compared with seven of 42 controls (P < 0.0001). Severe thrombocytopenia may be a useful indicator of systemic Candida infection in ELBW infants.
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BMJ · 1939 · 185 citations
Systemic candidiasis in very low-birth-weight infants (less than 1,500 grams).
Dana E. Johnson, Theodore R. Thompson, Thomas P. Green et al. · PubMed · 1984 · 174 citations