A distinct influenza infection signature in the blood transcriptome of patients with severe community-acquired pneumonia

Grant P. Parnell, Anthony S. McLean, David R. Booth, Nicola J. Armstrong, Marek Nalos, Stephen Huang, Jan Maňák, W.H. Wilson Tang, Oi-Yan Tam, Stanley Chan,

Critical Care · 2012 · 122 citations · 26 references

DOIFull text

Open access

Abstract

The whole-blood expression-profiling data indicate that the host response to influenza pneumonia is distinctly different from that caused by bacterial pathogens. This information may speed the identification of the cause of infection in patients presenting with severe respiratory failure, allowing appropriate patient care to be undertaken more rapidly.

References

26