Triterpenoid Saponins from <i>Rubus ellipticus</i> var. <i>obcordatus</i>

Wei Li, Hongwei Fu, Hong Bai, Tatsunori Sasaki, Hiroyoshi Kato, Kazuo Koike

Journal of Natural Products · 2009 · 77 citations · 20 references

Concepts

Abstract

Ten new triterpenoid saponins (1-10), named rubusides A-J, and 21 known saponins (11-31) were isolated from the roots of Rubus ellipticus var. obcordatus. The structures of 1-10 were established on the basis of spectroscopic analyses, mainly NMR and MS, and chemical degradations. The compounds demonstrated inhibitory activities against alpha-glucosidase with IC50 values in the range 0.65-3.09 mM.

References

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