Concepedia

Intracerebroventricular injection of propionic acid, an enteric metabolite implicated in autism, induces social abnormalities that do not differ between seizure-prone (FAST) and seizure-resistant (SLOW) rats

Sandy R. Shultz, Noor Abdul aziz, Li Yang, Mujun Sun, Derrick F. MacFabe, Terence J. O’Brien

Behavioural Brain Research · 2014 · 68 citations · 36 references

DOI

Concepts

References

36

Neuroglial activation and neuroinflammation in the brain of patients with autism

Diana Vargas, Caterina Nascimbene, Chitra Krishnan et al. · Annals of Neurology · 2004 · 2.1K citations

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Prevalence of autism spectrum disorders--autism and developmental disabilities monitoring network, 14 sites, United States, 2002.

PubMed · 2007 · 1.6K citations

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Neurobiological effects of intraventricular propionic acid in rats: Possible role of short chain fatty acids on the pathogenesis and characteristics of autism spectrum disorders

Derrick F. MacFabe, Donald P. Cain, Andrew E. Franklin et al. · Behavioural Brain Research · 2006 · 493 citations

, , +9

Short-chain fatty acid fermentation products of the gut microbiome: implications in autism spectrum disorders

Derrick F. MacFabe · Microbial Ecology in Health and Disease · 2012 · 424 citations · Full text

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Effects of the enteric bacterial metabolic product propionic acid on object-directed behavior, social behavior, cognition, and neuroinflammation in adolescent rats: Relevance to autism spectrum disorder

Derrick F. MacFabe, Nathan E. Cain, Francis Boon et al. · Behavioural Brain Research · 2010 · 358 citations

, , +14