Concepedia

Effect of Triiodothyronine Injection on Levels of Triiodothyronine and Thyroid-Stimulating Hormone in Sera and Milk of Lactating Rats and in Sera of Their Sucklings;Precocious Development of Jejunal α-Disaccharidases in the Sucklings

O. Koldovský, L. Krulich, Alfred Tenore, Jocelyn Jumawan, Carolyn Horowitz, H. Lau

Biology of the Neonate · 2009 · 14 citations · 0 references

Concepts

AgricultureBiochemistryEndocrinologyLactationLactation BiologyLactation PhysiologyLactation EndocrinologyThyroid Hormone BiochemistryEndocrine Regulation Of LactationEnzymatic Regulation Of Hormone LevelsGlycosidasesMaternal Endocrine Adaptation To LactationMetabolic Hormones In LactationThyroid Hormone PhysiologyThyroid Stimulating Hormone PhysiologyThyroid-stimulating Hormone Stimulation

Abstract

Administration of high doses of triiodothyronine (T3) for 4 days to lactating rats evokes an increase in T3 levels in their sera and milk, as well as in the sera of pups suckled by them. Thyroid-stimulating hormone levels in sera of mothers and sucklings are decreased. Suckling rats of T3-treated mothers exhibit a precocious increase in the activity of jejunal sucrase and maltase as well as in activity of several liver acid beta-glycosidases.