Transient suppression of tinnitus by transcranial magnetic stimulation

TLDR

Tinnitus has been linked to irregular activation of the temporoparietal cortex, suggesting that disrupting this area could transiently reduce symptoms. The study aimed to test whether 10‑Hz repetitive transcranial magnetic stimulation over the temporoparietal cortex could transiently suppress tinnitus in chronic patients. The authors delivered 10‑Hz rTMS to eight scalp sites and four control sites in 14 patients. Stimulation of the left temporoparietal cortex significantly reduced tinnitus, supporting a role for secondary auditory areas in tinnitus perception. Published in Annals of Neurology, 2003.

Abstract

Abstract It has been proposed that tinnitus is associated with an irregular activation of the temporoparietal cortex. If this activity is a functionally relevant component of the tinnitus‐related network, a virtual temporary lesion of this area should result in transient reduction of tinnitus. To test this hypothesis, we applied 10Hz repetitive transcranial magnetic stimulation to eight scalp and four control positions in 14 patients with chronic tinnitus. Stimulation of left temporoparietal cortex significantly reduced tinnitus (Friedman analysis of variance, p < 0.05; compared with control), indicating that secondary auditory areas can be critical for tinnitus perception, perhaps as a consequence of maladaptive cortical reorganization. Ann Neurol 2003