Cisplatin-encapsulated organic nanotubes by endo-complexation in the hollow cylinder

Abstract

A bipolar glycolipid self-assembles into organic nanotubes upon its chelation with an anticancer drug cis-dichlorodiamineplatinum(II) (CDDP). The facile synthesis of glycolipid, chelation-assisted formation of the nanotubes, and efficient loading and prolonged release of CDDP demonstrate a new approach to high-axial supramolecular drug nanocarriers.