Concepedia

Pulmonary Hypertension and Systemic Vasoconstriction May Offset the Benefits of Acellular Hemoglobin Blood Substitutes

Luiz Francisco Poli de Figueiredo, M. Mathru, Daneshvari R. Solanki, Victor W. Macdonald, John R. Hess, G. C. Kramer

1997 · 59 citations · 34 references

DOI

Abstract

Small-volume infusion of alpha alpha Hb restored mean arterial pressure and brain blood flow, but pulmonary hypertension and low peripheral perfusion may offset benefits for trauma patients.

References

34

Molecular mechanisms and therapeutic strategies related to nitric oxide

Salvador Moncada, E.A. Higgs · The FASEB Journal · 1995 · 780 citations

The Molecule of the Year

Ruth Levy Guyer, Daniel E. Koshland · Science · 1989 · 483 citations

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The Molecule of the Year

Daniel E. Koshland · Science · 1992 · 426 citations

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Systemic and pulmonary hypertension after resuscitation with cell-free hemoglobin

John R. Hess, Victor W. Macdonald, William W. Brinkley · Journal of Applied Physiology · 1993 · 306 citations

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A role for endothelin and nitric oxide in the pressor response to diaspirin cross-linked hemoglobin.

Scot C. Schultz, Bart Grady, F. E. Cole et al. · PubMed · 1993 · 220 citations