Concepedia

Computational prediction and experimental validation of low-affinity target of triptolide and its analogues

Xiufeng Liu, Kai Wang, Ningjun Duan, Lan Yan, Pengcheng Ma, Heng Zheng, Weijuan Zheng, Jiahuang Li, Zichun Hua

RSC Advances · 2015 · 16 citations · 28 references

DOI

Concepts

Abstract

ERα as a novel low affinity target for triptolide and its analogues triptonide and triptriolide.

References

28

The Estrogen Receptor Relative Binding Affinities of 188 Natural and Xenochemicals: Structural Diversity of Ligands

R. Blair · Toxicological Sciences · 2000 · 790 citations

Kinetic analysis of macromolecular interactions using surface plasmon resonance biosensors

David G. Myszka · Current Opinion in Biotechnology · 1997 · 550 citations

, , +5

Anti-inflammatory and immunosuppressive compounds from Tripterygium wilfordii

Jun Ma, Moul Dey, Hui Yang et al. · Phytochemistry · 2007 · 141 citations

, , +3

Human estrogen receptor forms multiple protein-DNA complexes.

Myles Brown, Phillip A. Sharp · Journal of Biological Chemistry · 1990 · 125 citations · Full text

, , +15

Thermodynamic benchmark study using Biacore technology

Iva Navrátilová, Giuseppe A. Papalia, Rebecca L. Rich et al. · Analytical Biochemistry · 2007 · 99 citations

, , +9