Medical Physics · 2003 · 246 citations · 18 references
MedicineRadiation OncologyRadiologyRadiation DosimetryRadiation MeasurementTreatment PlanningDose CalibrationDosimetry InstrumentationExternal Beam DosimetryIntensity-modulated RadiotherapyRadiation Dose MeasurementRadiation TherapyAmorphous SiliconDead Time EffectsDosimetric CalibrationExternal Beam Radiotherapy DosimetryFrame AcquisitionIntensity ModulationIntensity-modulated Radiation Therapy DosimetryLinearity
Dosimetric properties of an amorphous silicon electronic portal imaging device (EPID) for verification of dynamic intensity modulated radiation therapy (IMRT) delivery were investigated. The EPID was utilized with continuous frame-averaging during the beam delivery. Properties studied included effect of buildup, dose linearity, field size response, sampling of rapid multileaf collimator (MLC) leaf speeds, response to dose-rate fluctuations, memory effect, and reproducibility. The dependence of response on EPID calibration and a dead time in image frame acquisition occurring every 64 frames were measured. EPID measurements were also compared to ion chamber and film for open and wedged static fields and IMRT fields. The EPID was linear with dose and dose rate, and response to MLC leaf speeds up to 2.5 cm s(-1) was found to be linear. A field size dependent response of up to 5% relative to dmax ion-chamber measurement was found. Reproducibility was within 0.8% (1 standard deviation) for an IMRT delivery recorded at intervals over a period of one month. The dead time in frame acquisition resulted in errors in the EPID that increased with leaf speed and were over 20% for a 1 cm leaf gap moving at 1.0 cm s(-1). The EPID measurements were also found to depend on the input beam profile utilized for EPID flood-field calibration. The EPID shows promise as a device for verification of IMRT, the major limitation currently being due to dead-time in frame acquisition.
18
Chandra Burman, Chen‐Shou Chui, Gerald J. Kutcher et al. · International Journal of Radiation Oncology*Biology*Physics · 1997 · 303 citations
Dosimetric verification of intensity‐modulated fields
Xiaohong Wang, Spiridon V. Spirou, T LoSasso et al. · Medical Physics · 1996 · 187 citations
Testing of dynamic multileaf collimation
Chen‐Shou Chui, Spiridon V. Spirou, T LoSasso · Medical Physics · 1996 · 172 citations