Alkylating properties and genetic activity of 4-vinylcyclohexene metabolites and structurally related expoxides

Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test

Bruce N. Ames, Joyce McCann, Edith F. Yamasaki · Mutation Research/Environmental Mutagenesis and Related Subjects · 1975 · 7.4K citations

Pharmacy, Toxicology, Carcinogenesis +7

Chemical Mutagens. Principles and Methods for Their Detection.

Annals of Internal Medicine · 1974 · 1.5K citations

Pharmacy, Microbiology, Toxicology +17

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

A. Loveless · Nature · 1969 · 948 citations

Pharmacy, Pharmacology, Toxicology +14

The production of micronuclei from chromosome aberrations in irradiated cultures of human lymphocytes

Paul I. Countryman, John A. Heddle · Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis · 1976 · 814 citations

Life Sciences, Cell Biology, Genetics +16

Quantitative Correlation of Relative Rates. Comparison of Hydroxide Ion with Other Nucleophilic Reagents toward Alkyl Halides, Esters, Epoxides and Acyl Halides¹

C. Gardner Swain, C. Scott · Journal of the American Chemical Society · 1953 · 627 citations

Natural Sciences, Chemistry, Analytical Chemistry +6