Effects of cyclooxygenase inhibitors flunixin and deracoxib on permeability of ischaemic‐injured equine jejunum

Abstract

Treatment of horses with ischaemic jejunal disease with flunixin may result in a prolonged permeability defect in recovering mucosa. Addition of misoprostol or replacement of flunixin with deracoxib may ameliorate effects of COX inhibitors on recovering mucosa.