Pediatric Neurosurgery · 1981 · 26 citations · 0 references
MedicineCardiologyPediatricsDevelopmental PediatricsEmbryologyPediatric CardiologyCongenital AnomaliesCongenital Heart DiseaseCongenital MalformationsDandy-walker MalformationFetal AnomaliesSeptal DefectsCardiac Developmental DefectsCentral Nervous System AbnormalitiesCongenital Cardiac AnomaliesCongenital Cardiovascular MalformationsFetal Cardiovascular MalformationsSeptal Defect EmbryologySeptal Developmental AnomalyTiming
2 patients with Dandy-Walker malformations (DWM) and cardiac anomalies are presented. The types of cardiac defects with septal involvement are suggestive of an early embryonic abnormality occurring before 6 weeks' gestational age. This correlates with the postulated timing of the development of the DWM and suggests a complex developmental anomaly. Awareness of the associated systemic and central nervous system anomalies in patients with the DWM in regard to management and prognosis is emphasized.