Synthesis · 2004 · 11 citations · 0 references
Natural SciencesChemistryCatalysisOrganic ChemistryCarbonyl ChemistryCarboxylic AcidsCarboxylic DerivativesFunctional GroupsOrganic SynthesisAliphatic Carboxylic AcidsAromatic Carbonyl ChemistryCarbonyl ReductionCarboxylic Derivative ReductionOrganic Reduction ReactionsOxidation Of Alcohols To Carbonyl CompoundsReduction Of Carboxylic Acids
A direct exhaustive reduction of aliphatic carbonyl functions (aldehydes, acyl chlorides, esters and carboxylic acids) to a methyl group by triethylsilane (Et3SiH) in the presence of catalytic amount of tris(pentafluorophenyl)borane [B(C6F5)3] is described. Aromatic carbonyl functions could undergo partial reduction to the corresponding TES-protected benzylic alcohols.