Publication | Closed Access
Synthesis of Substituted Dicyanomethylendihydrofurans
102
Citations
5
References
1995
Year
Room TemperatureDerivative (Chemistry)Enantioselective SynthesisDerivativesHeterocyclicEfficient MethodA SimpleNatural SciencesDiversity-oriented SynthesisOrganic ChemistryChemistryPharmacologyChemical DerivativeSynthetic ChemistrySubstituted DicyanomethylendihydrofuransNatural Product Synthesis
Abstract A simple and efficient method for the preparation of the title compounds is described from α-ketols and malononitrile in the presence of sodium ethylate at room temperature. These compounds lead to unsaturated derivatives by condensation with aldehydes.
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