Organic Letters · 2005 · 95 citations · 39 references
Natural SciencesChemical EngineeringChemistryCatalysisOrganic ChemistryCatalyst DesignCatalyst PreparationCatalyst SynthesisCatalytic MaterialsCatalytic MechanismsSupported CatalystsCatalyst Structure - Activity RelationshipsEnantioselective CatalysisEnantioselective SynthesisEnantioselectivityLewis Acidity
The first example of enantioselective ring-opening reaction of meso-epoxides with aryl selenols to give optically active beta-arylseleno alcohol in up to 97% ee was realized, using a chiral Ti-Ga-Salen heterometallic catalyst. A strong synergistic effect of different Lewis acids in the system was exhibited in the catalytic process.
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