The Inhibitory Action of a Compound Obtained from Hip Seeds (HSC) on the Release of Histamine and the Disruption of Nast Cells Produced by Compound 48/80 and Extracts from Jellyfish (Cyanea Capillata) and Eelworm of Swine (Ascaris Lumbricoides)

Abstract

Summary. Hip seed extracts prepared by repeated precipitation with alcohol or trirhloracetic acid extraction and barium fractionation were observed to block: (1)The histamine liberation produced in perfused cat's paw by 48/80 and by extracts from jellyfish ( Cyanea capillata ) and the eelworm of swine ( Ascaris lumbricoides ). (2) The rupture of mast cells produced by the same three agents.