Some observations on Paget's disease of the nipple

Abstract

HE ASSOCIATION of an eczematous condi-T tion of the nipple with a cancer of the terminal part of one or more lactiferous ducts -commonly known as Paget's disease of the nipple-has provided the stimulus for much investigation and speculation. Through the work of Muir,4 Inglis,3 and others, our present concepts of this condition have evolved. T h e Paget cells are regarded as migrant cancer cells derived frorn the growth in the terminal part of the lactiferous duct(s), which have invaded the epidermis by direct continuity (Fig.