Archives of Dermatology · 2008 · 60 citations · 23 references
MedicineDermatologyPathologyAnatomic PathologyDermatopathologyHistopathologyInflammatory DermatosesPigmentary DisordersVascular PathologyVascular Skin LesionsCutaneous Blood VesselsPustular Lesions
BACKGROUND: A possible association between lichen aureus (LA) and mycosis fungoides (MF) has been suggested in the past. We evaluated the clinicopathologic features of LA and its relationship to MF. Data from 23 patients with a clinicopathologic diagnosis of LA were reviewed. OBSERVATIONS: Lesions were asymmetrically localized on 1 area of the body (mostly 1 extremity) and were characterized histologically by dense, bandlike lymphocytic infiltrates. A monoclonal T-cell population was detected in half of the cases. After a mean follow-up of 102.1 months, 14 patients had no sign of skin disease, 7 patients had unmodified skin lesions, and 2 other patients with unmodified skin lesions had died of unrelated conditions. Treatment modalities did not affect the outcome. There was no relationship between the presence or absence of monoclonality and patient status at follow-up assessments. Conclusion Patients with classic lesions of LA do not show progression to MF.
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A simplified method of detection of clonal rearrangements of the T-cell receptor-gamma chain gene.
Keith McCarthy, J P Sloane, Janusz H. Kabarowski et al. · PubMed · 1992 · 259 citations
Life Sciences, Immunology, Pathology +17
Lorenzo Cerroni, Regina Fink‐Puches, Barbara Bäck et al. · Archives of Dermatology · 2002 · 210 citations
Medicine, Dermatology, Pathology +17