Herpes simplex virus type 1 mutant HF10 oncolytic viral therapy for bladder cancer

Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial

James M. Markert, Michael D. Medlock, Samuel D. Rabkin et al. · Gene Therapy · 2000 · 971 citations

Neuro-oncology, Cancer-associated Virus, Glioma +8

Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma

R Rampling, G. Cruickshank, Vakis Papanastassiou et al. · Gene Therapy · 2000 · 594 citations

Neuro-oncology, Null Mutant 1716, Medicine +11

Herpes simplex virus type 1-induced ribonucleotide reductase activity is dispensable for virus growth and DNA synthesis: isolation and characterization of an ICP6 lacZ insertion mutant

D. Goldstein, Sandra K. Weller · Journal of Virology · 1988 · 394 citations · Full text

Viral Replication, Molecular Biology, Viral Structural Protein +18

Infections with Herpes Simplex Viruses

Lawrence Corey, Patricia G. Spear · New England Journal of Medicine · 1986 · 380 citations

Diagnostic Virology, Viral Persistence, Viral Diagnostics +14

The potential for efficacy of the modified (ICP 34.5−) herpes simplex virus HSV1716 following intratumoural injection into human malignant glioma: a proof of principle study

Vakis Papanastassiou, R Rampling, Matthew Fraser et al. · Gene Therapy · 2002 · 326 citations

Neuro-oncology, Cancer-associated Virus, Immunology +10