Hydrogen Bonding. 33. Factors That Influence the Distribution of Solutes between Blood and Brain

The use of characteristic volumes to measure cavity terms in reversed phase liquid chromatography

Michael H. Abraham, J. C. McGowan · Chromatographia · 1987 · 856 citations

Supercritical Fluid Chromatography, Separation Science, Cavity Terms +7

Development of a new physicochemical model for brain penetration and its application to the design of centrally acting H2 receptor histamine antagonists

Rodney C. Young, Robert Cameron Mitchell, Thomas H. Brown et al. · Journal of Medicinal Chemistry · 1988 · 517 citations

Brain Penetration, Rational Approach, Anesthetic Mechanism +19

Hydrogen bonding. Part 10. A scale of solute hydrogen-bond basicity using log K values for complexation in tetrachloromethane

Michael H. Abraham, Priscilla L. Grellier, David V. Prior et al. · Journal of the Chemical Society Perkin Transactions 2 · 1990 · 433 citations

Hydrogen bonding. Part 7. A scale of solute hydrogen-bond acidity based on log K values for complexation in tetrachloromethane

Michael H. Abraham, Priscilla L. Grellier, David V. Prior et al. · Journal of the Chemical Society Perkin Transactions 2 · 1989 · 350 citations

Engineering, Acid-base Chemistry, Chemistry +17

Hydrogen bonding. 31. Construction of a scale of solute effective or summation hydrogen‐bond basicity

Michael H. Abraham · Journal of Physical Organic Chemistry · 1993 · 345 citations

Solute Hydrogen‐bond Basicity, Engineering, Molecular Thermodynamics +15