Peripheral administration of novel anti-inflammatories can attenuate the effects of chronic inflammation within the CNS

Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease.

W. Sue T. Griffin, Laura Stanley, Lon R. White et al. · Proceedings of the National Academy of Sciences · 1989 · 1.8K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Clinical trial of indomethacin in Alzheimer's disease

Jospeh Rogers, L. Kirby, S. R. Hempelman et al. · Neurology · 1993 · 999 citations

Medicine, Neurology, Pharmacology +15

Gastrointestinal Damage Associated with the Use of Nonsteroidal Antiinflammatory Drugs

M C Allison, Allan G. Howatson, Caroline J. Torrance et al. · New England Journal of Medicine · 1992 · 962 citations · Full text

Medicine, Internal Medicine, Pharmacology +11

Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR

Patrick L. McGeer, Shigeru Itagaki, Hisao Tago et al. · Neuroscience Letters · 1987 · 836 citations

Life Sciences, Immunology, Neuroscience +14

Activation of the classical complement pathway in brain tissue of Alzheimer patients

Patrick L. McGeer, Haruhiko Akiyama, Shigeru Itagaki et al. · Neuroscience Letters · 1989 · 388 citations

Life Sciences, Neurobiology, Neuroscience +15