Efficient Retrograde Neuronal Transduction Utilizing Self-complementary AAV1

Production of High-Titer Recombinant Adeno-Associated Virus Vectors in the Absence of Helper Adenovirus

Xiao Xiao, Juan Li, R. Jude Samulski · Journal of Virology · 1998 · 1.4K citations · Full text

Retrograde Viral Delivery of IGF-1 Prolongs Survival in a Mouse ALS Model

Brian K. Kaspar, Jerònia Lladó, Nushin Sherkat et al. · Science · 2003 · 863 citations

Viral Pathogenesis, Immunology, Biomedical Engineering +16

Recombinant AAV Viral Vectors Pseudotyped with Viral Capsids from Serotypes 1, 2, and 5 Display Differential Efficiency and Cell Tropism after Delivery to Different Regions of the Central Nervous System

Corinna Bürger, Oleg S. Gorbatyuk, Margaret J. Velardo et al. · Molecular Therapy · 2004 · 732 citations · Full text

Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis

DM McCarty, PE Monahan, RJ Samulski · Gene Therapy · 2001 · 706 citations

Engineering, Dna Synthesis, Genetic Engineering +9

Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo

Douglas M. McCarty, Haiyan Fu, Paul E. Monahan et al. · Gene Therapy · 2003 · 533 citations

Viral Replication, Medicine, Natural Sciences +11