Competitive interactions at [3H]1,3-DI(2-tolyl) guanidine (DTG)-defined σ recognition sites in guinea pig brain

Analysis of radioligand binding experiments

Grant A. McPherson · Journal of Pharmacological Methods · 1985 · 1.2K citations

Natural Sciences, Biochemistry, Chemistry +9

Structural determinants of sigma receptor affinity.

B L Largent, Håkan Wikström, Andrew L. Gundlach et al. · Molecular Pharmacology · 1987 · 128 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Labeling by [3H]1,3-di(2-tolyl)guanidine of two high affinity binding sites in guinea pig brain: evidence for allosteric regulation by calcium channel antagonists and pseudoallosteric modulation by sigma ligands.

RB Rothman, Audrey A. Reid, Artin Mahboubi et al. · Molecular Pharmacology · 1991 · 112 citations

Medicine, Neurobiology, Pharmacology +10

The sigma receptor: a novel site implicated in psychosis and antipsychotic drug efficacy.

Stephen I. Deutsch, Abraham Weizman, Mark E. Goldman et al. · PubMed · 1988 · 83 citations

Medicine, Neuroscience, Pharmacology +12

The Sigma Receptor

Stephen I. Deutsch, Abraham Weizman, Mark E. Goldman et al. · Clinical Neuropharmacology · 1988 · 77 citations

Life Sciences, Molecular Biology, Cell Signaling +3