Cyclohexy (4-fluorophenyl)(3-piperidinopropyl)silanol ((itp)-fluoro-hexahydro-sila-difenidol, p-F-HSSiD) and derivatives: synthesis and antimuscarinic properties

Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells.

Noel J. Buckley, T I Bonner, C M Buckley et al. · Molecular Pharmacology · 1989 · 634 citations · Full text

Medicine, Pharmacology, Cellular Pharmacology +14

Antagonist binding profiles of five cloned human muscarinic receptor subtypes.

Frank Dörje, J. Wess, G. Lambrecht et al. · Journal of Pharmacology and Experimental Therapeutics · 1990 · 612 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

p-fluoro-hexahydro-sila-difenidol: The first M2β-selective muscarinic antagonist

Günter Lambrecht, Roland Feifel, Bernhard Forth et al. · European Journal of Pharmacology · 1988 · 129 citations

Medicine, Medicinal Chemistry, Pharmacology +8

Differential coupling of subtypes of the muscarinic receptor to adenylate cyclase and phosphoinositide hydrolysis in the longitudinal muscle of the rat ileum.

L M Candell, Sanggeon Yun, Louise Tran et al. · Molecular Pharmacology · 1990 · 114 citations

Medicine, Pharmacology, General Pharmacology +13

Affinity profiles of hexahydro-sila-difenidol analogues at muscarinic receptor subtypes

Günter Lambrecht, Roland Feifel, Monika Wagner-Röder et al. · European Journal of Pharmacology · 1989 · 105 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16