Concepedia

Toxicity of platinum(II) amino acid (N,O) complexes parallels their binding to DNA as measured in a new solid phase assay involving a fluorescent HMG1 protein construct readout

Christopher J. Ziegler, Karen E. Sandman, Cynthia H. Liang, Stephen J. Lippard

JBIC Journal of Biological Inorganic Chemistry · 1999 · 13 citations · 0 references

Concepts

PharmacyBiochemistryMolecular BiologyMechanisms Of ToxicityMolecular ToxicologyProtein BiochemistryDna ChemistryDna DamageLigand BindingMolecular Mechanisms Of ToxicityPlatinum CompoundsPlatinum-based Agents