The effect of fentanyl and clonidine on early postoperative negative behavior in children: a double‐blind placebo controlled trial

Abstract

IV fentanyl before surgery but not IV clonidine modifies e-PONB in children undergoing lower abdominal surgery under general anesthesia supplemented with regional anesthesia. The use of fentanyl in this population was also associated with reduced pain scores after awakening but with significantly greater incidence of PONV.