Dual-Color Click Beetle Luciferase Heteroprotein Fragment Complementation Assays

β‐catenin is a target for the ubiquitin–proteasome pathway

Hermann Aberle, Andreas Bauer, Jörg Stappert et al. · The EMBO Journal · 1997 · 2.5K citations

Life Sciences, Cell Biology, Molecular Biology +7

The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest.

Cheng‐Ting Chien, Paul L. Bartel, Rolf Sternglanz et al. · Proceedings of the National Academy of Sciences · 1991 · 1.5K citations

Life Sciences, Genetics, Molecular Biology +13

Split ubiquitin as a sensor of protein interactions in vivo.

Nils Johnsson, Alexander Varshavsky · Proceedings of the National Academy of Sciences · 1994 · 787 citations

Life Sciences, Biochemistry, Molecular Biology +16

Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis

Chang-Deng Hu, Tom K. Kerppola · Nature Biotechnology · 2003 · 783 citations · Full text

Natural Sciences, Biophysics, Cell Biology +13

Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin.

Barbara E. Bierer, Petri S. Mattila, Robert F. Standaert et al. · Proceedings of the National Academy of Sciences · 1990 · 708 citations

Life Sciences, Immunology, Pharmacology +16