Chemical Communications · 2010 · 29 citations · 11 references
MedicineMicrobiologyPharmacologyAntimicrobial PharmacologyAntimicrobial ResistanceIon Channel BiophysicsAntibiotic ResistanceAntimicrobial ToxicityIon Channel PharmacologyIon Channel PhysiologyIon Channel ToxicityIon ChannelsBacillus SubtilisDrug Binding To Ion ChannelsEscherichia ColiIon Channel EngineeringIon Channel Structure-function RelationshipsIon Channel-mediated Toxicity
Hydraphile synthetic ion channels were found to enhance the cytotoxicity to E. coli and B. subtilis of erythromycin, kanamycin, rifampicin, and tetracycline when co-administered with the antibiotic at sublethal concentrations of channel.
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