Journal of Hand Surgery (European Volume) · 2004 · 51 citations · 22 references
MedicinePharmacotherapySurgeryGeneral Internal MedicineHemostasisVascular SurgeryAnticoagulant ManagementAnticoagulant TherapyAnticoagulation ManagementAnticoagulation TherapyThrombosisThrombosis ManagementAnticoagulant-related Bleeding ComplicationsCoagulationHospital Stay DurationManagement Of Bleeding ComplicationsPerioperative Anticoagulant ManagementPostoperative HemostasisProlonged Length Of StayTherapeutic Anticoagulation
Interruption of appropriate therapeutic warfarin therapy imposes a risk of morbidity and mortality on the patient. Strategies to reduce the risks of interruption impose relatively large costs in terms of prolonged hospital stay, medication and coagulation monitoring. We report a series of 47 consecutive surgical episodes on the hands of 39 patients without interruption of therapeutic warfarin anticoagulation and with an INR of between 1.3 and 2.9. There was no difficulty with intraoperative haemostasis. Two patients had minor bleeding-related complications with no long-term sequelae. The authors conclude that interruption to warfarin therapy is unnecessary if the INR is less than 3.0 and therefore inappropriate for therapeutically anticoagulated patients undergoing hand surgery.
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British Journal of Diseases of the Chest · 1984 · 500 citations
Mark Levine, Jack Hirsh, Michael Gent et al. · Thrombosis and Haemostasis · 1995 · 357 citations
The bleeding time does not predict surgical bleeding [see comments]