Antidepressant-like effect of 7-nitroindazole in the forced swimming test in rats

Depression: a new animal model sensitive to antidepressant treatments

Roger D. Porsolt, Manuel Pichon, M Jalfre · Nature · 1977 · 4.4K citations

Medicine, Neuroscience, Psychiatry +12

Functional antagonists at the NMDA receptor complex exhibit antidepressant actions

Ramón Trullás, P. Skolnick · European Journal of Pharmacology · 1990 · 777 citations

Medicine, Neuroscience, Pharmacology +12

Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex

Sizheng Z. Lei, Zhuo-Hua Pan, Sanjay K. Aggarwal et al. · Neuron · 1992 · 749 citations

Life Sciences, Neurobiology, Neuroscience +16

Anticonvulsant activity of (+)‐5‐methyl‐10, 11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

Bradley V. Clineschmidt, Gregory E. Martin, Patricia R. Bunting · Drug Development Research · 1982 · 498 citations

Medicine, Neurology, Pharmacology +12

Nitric oxide-induced blockade of NMDA receptors

Olivier J. Manzoni, Laurent Prézeau, Philippe Marin et al. · Neuron · 1992 · 452 citations

Medicine, Neurobiology, Neuroscience +12