Concepedia

Transgenic avian-derived recombinant human interferon-a2b (AVI-005) in healthy subjects: an open-label, single-dose, controlled study

Tarun B. Patel, E Péquignot, Steven Parker, Mark C. Leavitt, Howard Greenberg, Walter K. Kraft

International Journal of Clinical Pharmacology and Therapeutics · 2007 · 10 citations · 9 references

DOI

Abstract

AVI-005 demonstrates biological activity and pharmaco-kinetic properties in humans that support further development.

References

9

Peginterferon Alfa-2a, Lamivudine, and the Combination for HBeAg-Positive Chronic Hepatitis B

George Lau, Teerha Piratvisuth, Kang Luo et al. · New England Journal of Medicine · 2005 · 1.5K citations · Full text

Pegylated interferon-α2b: Pharmacokinetics, pharmacodynamics, safety, and preliminary efficacy data

Paul Glue · Clinical Pharmacology & Therapeutics · 2000 · 506 citations

Activation of the protein kinase PKR by short double-stranded RNAs with single-stranded tails

Xiaofeng Zheng, Philip C. Bevilacqua · RNA · 2004 · 102 citations · Full text

, , +20

Use of an indirect pharmacodynamic stimulation model of MX protein induction to compare in vivo activity of interferon alfa-2a and a polyethylene glycol-modified derivative in healthy subjects

Keith Nieforth, R Nadeau, Indravadan H. Patel et al. · Clinical Pharmacology & Therapeutics · 1996 · 84 citations

Effects of interferon-alpha (IFN-α) administration on leucocytes in healthy humans

E. P. M. Corssmit, Rik Heijligenberg, C. Erik Hack et al. · Clinical & Experimental Immunology · 1997 · 69 citations · Full text