Concepedia

Four cases of invasive methicillin-resistant Staphylococcus aureus (MRSA) infections treated with tigecycline

L. Silvia Muñoz-Price, Karen Lolans, John P. Quinn

Scandinavian Journal of Infectious Diseases · 2006 · 25 citations · 6 references

DOI

Concepts

Abstract

We report 4 cases of invasive methicillin-resistant Staphylococcus aureus (MRSA) infections who received treatment with tigecycline after unsuccessful treatment attempts with conventional drugs. All 4 patients were eventually cured although 1 experienced a relapse of her bacteremia while on treatment due to inadequate dosing.

References

6

Pharmacokinetics of Tigecycline after Single and Multiple Doses in Healthy Subjects

G. Muralidharan, Marlynne Micalizzi, John Speth et al. · Antimicrobial Agents and Chemotherapy · 2004 · 336 citations · Full text

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In vitro activity of tigecycline against 6792 Gram-negative and Gram-positive clinical isolates from the global Tigecycline Evaluation and Surveillance Trial (TEST Program, 2004)

Daryl J. Hoban, Samuel K. Bouchillon, Brian Johnson et al. · Diagnostic Microbiology and Infectious Disease · 2005 · 205 citations

, , +7

Safety and Efficacy of Tigecycline in Treatment of Skin and Skin Structure Infections: Results of a Double-Blind Phase 3 Comparison Study with Vancomycin-Aztreonam

Johannes Breedt, Jüri Teras, Jānis Gardovskis et al. · Antimicrobial Agents and Chemotherapy · 2005 · 191 citations · Full text

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Persistence in Staphylococcus aureus bacteremia: Incidence, characteristics of patients and outcome

Riad Khatib, Leonard B. Johnson, Mohamad G. Fakih et al. · Scandinavian Journal of Infectious Diseases · 2005 · 165 citations

, , +17

Tigecycline MIC Testing by Broth Dilution Requires Use of Fresh Medium or Addition of the Biocatalytic Oxygen-Reducing Reagent Oxyrase To Standardize the Test Method

Patricia A. Bradford, Peter J. Petersen, Mairead Young et al. · Antimicrobial Agents and Chemotherapy · 2005 · 114 citations

, , +14