Predictors of Fatal and Non-Fatal Outcomes in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA): Incremental Value of Apolipoprotein A-1, High-Sensitivity C-Reactive Peptide and N-terminal pro B-type Natriuretic Peptide

Abstract

Of the two new biomarkers studied in prognostic models in heart failure, NT-proBNP, but not hsCRP, added substantial and independent predictive information, for a range of clinical outcomes, to that provided by simple demographic, clinical, and biochemical measures. ApoA-1 was more predictive than LDL or HDL.