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Drug repurposing: sulfasalazine sensitizes gliomas to gamma knife radiosurgery by blocking cystine uptake through system Xc−, leading to glutathione depletion

Neuro-oncologyRadiation MedicineRadiation TherapyGliomaMedicinePharmacologyKnife RadiosurgeryPharmacotherapyAnti-cancer AgentCancer TreatmentOncologyRadiation OncologyCystine UptakeDrug RepurposingDrug Discovery