Therapeutic Advances in Psychopharmacology · 2013 · 10 citations · 9 references
NursingPharmacologyPharmacotherapyClinical PharmacologyPsychopharmacologySubstance Use DisordersAddictionCannabis Use DisorderDrug DependenceSubstance UseSubstance WithdrawalWithdrawal SyndromesCannabinoid WithdrawalClinical Utility AnalysisClinical Utility AssessmentPharmacologic Treatment Of WithdrawalPharmacological Management Of WithdrawalSubjective Drug EffectsSubstance Use Disorder PharmacotherapyWithdrawal Symptoms
Cannabis is the most commonly used illicit drug in the world. However, only few studies have shown the efficacy of pharmacologic agents in targeting cannabis withdrawal symptoms or reducing the reinforcing effects of cannabis. Baclofen has been shown to reduce cannabis withdrawal symptoms and the subjective effects of cannabis. We think that the clinical utility of baclofen for cannabis dependence is a reasonable approach. A case report using baclofen is presented and provides preliminary support for the use of baclofen in the management of cannabis dependence.
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The natural course of cannabis use, abuse and dependence during the first decades of life
Axel Perkonigg, Renée D. Goodwin, Agnes Fiedler et al. · Addiction · 2008 · 176 citations