Concepedia

GRP78 counteracts cell death and protein aggregation caused by mutant huntingtin proteins

Yufeng Jiang, Hailong Lv, Min Liao, Xiaoyuan Xu, Shanshan Huang, Huiping Tan, Ting Peng, Yinong Zhang, Li He

Neuroscience Letters · 2012 · 42 citations · 24 references

DOI

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References

24

Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain

Marian DiFiglia, Ellen Sapp, Kathryn Chase et al. · Science · 1997 · 2.9K citations

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Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation

Stephen W. Davies, Mark Turmaine, Barbara A. Cozens et al. · Cell · 1997 · 2.2K citations · Full text

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Reversal of Neuropathology and Motor Dysfunction in a Conditional Model of Huntington's Disease

Ai Yamamoto, José J. Lucas, René Hen · Cell · 2000 · 1.1K citations · Full text

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Role of the Unfolded Protein Response Regulator GRP78/BiP in Development, Cancer, and Neurological Disorders

Miao Wang, Shiuan Wey, Yi Zhang et al. · Antioxidants and Redox Signaling · 2009 · 605 citations · Full text

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Endoplasmic Reticulum Chaperones GRP78 and Calreticulin Prevent Oxidative Stress, Ca2+ Disturbances, and Cell Death in Renal Epithelial Cells

Hong Liu, Russell C. Bowes, Bob van de Water et al. · Journal of Biological Chemistry · 1997 · 373 citations · Full text

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