An EF-hand in the sodium channel couples intracellular calcium to cardiac excitability

Basic local alignment search tool

Stephen F. Altschul, Warren Gish, Webb Miller et al. · Journal of Molecular Biology · 1990 · 94.5K citations

Life Sciences, Bioinformatics, Sequence Analysis +3

PROCHECK: a program to check the stereochemical quality of protein structures

Roman A. Laskowski, Malcolm W. MacArthur, D. S. Moss et al. · Journal of Applied Crystallography · 1993 · 24.6K citations

Life Sciences, Biochemistry, Bioinformatics +9

Mortality and Morbidity in Patients Receiving Encainide, Flecainide, or Placebo

Debra S. Echt, Philip R. Liebson, L. Brent Mitchell et al. · New England Journal of Medicine · 1991 · 3.3K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures

Roger Y. Tsien · Biochemistry · 1980 · 2.2K citations

Natural Sciences, Biochemistry, Chemistry +11

Genetic basis and molecular mechanism for idiopathic ventricular fibrillation

Qiuyun Chen, Glenn E. Kirsch, Danmei Zhang et al. · Nature · 1998 · 1.8K citations

Medicine, Cardiology, Genetics +16