International Journal of Dermatology · 1992 · 14 citations · 7 references
MedicineDermatologySurgeryHistopathologyHypersensitivityImmunopathologyAutoimmune Skin DiseasesImmunopathology Of SkinInflammatory DermatosesInflammatory LesionsInflammatory Skin DiseasesInflammatory Skin DisordersCutaneous Immune ResponseCutaneous Immune-mediated DiseaseCutaneous ImmunologyDisorderImmune-mediated DermatitisPerivascular PathologySuperficial Perivascular Dermatitis
Behçet's Disease (BD) is a systemic disorder with an unknown etiopathogenesis. The need for clinical criteria in the establishment of diagnosis is of great importance. We present the case of a 27-year-old man with BD, who had a surgical operation during the active period of his disease and experienced subsequent complications. Cutaneous hyper-reactivity response to minor cutaneous trauma--the pathergy phenomenon--is found in most patients with BD. Theoretically, major traumas may lead to major reactions in the skin or any of the organs. In practice, we observed that while there was a severe inflammatory reaction--histopathologically a superficial perivascular dermatitis--which developed at the incision site, the systemic symptoms of the disease increased in spite of intensive treatment of the condition.
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Use of colchicine in Behçet's syndrome.
Hans M. Sander, H. W. Randle · PubMed · 1986 · 28 citations
Medicine, Immunology, Pharmacology +10