Concepedia

Circulating Endothelial Progenitor Cells in Patients With Eisenmenger Syndrome and Idiopathic Pulmonary Arterial Hypertension

Gerhard‐Paul Diller, Sven van Eijl, Darlington O. Okonko, Luke Howard, Thomas Thum, Stephen J. Wort, Élisabeth Bédard, J. Simon R. Gibbs, Johann Bauersachs, Adrian J. Hobbs,

Circulation · 2008 · 224 citations · 41 references

DOIFull text

Open access

Abstract

Circulating EPC numbers are reduced in 2 well-characterized forms of PAH, which also exhibit raised levels of inflammatory mediators. Sildenafil treatment may represent a pharmacological means of increasing circulating EPC numbers long-term.

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