Pathological Review of Wilms Tumor Nephrectomy Specimens and Potential Implications for Nephron Sparing Surgery in Wilms Tumor

Abstract

In a post hoc analysis using strict pathological criteria and accepted surgical oncologic principles, as many as 1 in 4 children undergoing pre-chemotherapy surgery for nonmetastatic, unilateral Wilms tumor have post-resection pathological tumor characteristics favorable for nephron sparing surgery.